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Psilocybin in Florida: a dated timeline, 1970 to 2027

Psilocybin is a Schedule I drug in Florida today, and nothing on this timeline has changed that. Here are the 85 dated events that shaped the law, the research and the enforcement around it, each with the source we checked.

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On this page
  1. What the timeline shows
  2. What were the big turning points?
  3. The full timeline
  4. What's coming up?
  5. How is the timeline maintained?
  6. Questions people ask
  7. Sources

What the timeline shows

It shows a state that has never loosened its psilocybin law. Florida's drug schedules list psilocybin and psilocyn in Schedule I today, as the federal schedules have since 1970.12 Every Florida bill since 2019 that would have opened a path to psilocybin therapy or a state study died, and no request for psilocybin research money made it into a final budget.568

The timeline lists 85 events from October 27, 1970 to March 2, 2027, sorted into five kinds: 17 laws, 13 court decisions, 29 policy moves (bills, budgets, agency guidance and ballots), 17 research milestones and 9 enforcement actions. Most are in Florida; others are federal or out-of-state events that change what Floridians can legally do, such as Oregon's and Colorado's licensed programs. Six are scheduled, not yet past, and say "Scheduled" at the start.

What were the big turning points?

1970 to 1978: the schedules, then Fiske

The Controlled Substances Act, enacted October 27, 1970, put psilocybin and psilocyn in federal Schedule I, and the history note to Florida's drug schedules, section 893.03, begins with ch. 73-331 (1973).12 On December 21, 1978 the Florida Supreme Court decided Fiske v. State, reversing one wild-mushroom conviction 4-3 because the statute gave that defendant no fair warning, while saying there is "no vagueness problem with the statute on its face."3 Our Fiske guide explains why that didn't legalize anything.

2002 and 2012: knowledge becomes a defense

In 2002 Florida made lack of knowledge of a drug's illicit nature an affirmative defense rather than something the State must prove, and the Florida Supreme Court rejected a facial due process challenge to it in 2012. Neither the statute nor that ruling mentions Fiske, and we found no court decision saying how they fit together.4

2021 to 2025: bills die, and the one new law restricts

Only three Florida bills filed from 2019 through 2026 were about psilocybin or psychedelic therapy: HB 549 (2021), which would have created a licensed psilocybin services program, and HB 193 and SB 348 (2022), which would have ordered a state study of MDMA, psilocybin and ketamine. All three died in their first committee.56 A $3,000,000 request for a USF psilocybin trial in veterans with PTSD reached the Senate's 2024 budget at $650,000 but not the final budget, and a 2025 request went nowhere.78 The one psilocybin-related law the Legislature did pass went the other way: since July 1, 2025, transporting, importing, selling or giving away mushroom spores or mycelium that will produce psilocybin is a first-degree misdemeanor.9

2023 to 2026: trials in Miami, products in shops

Late-stage psilocybin trials came to South Florida, including COMPASS Pathways' trials with Miami-area sites and a PTSD study listing a Miami site in 2026.10 FDA granted Breakthrough Therapy designations to psilocybin in 2018 and 2019 and national priority vouchers in April 2026, while stressing that neither is a finding of safety or effectiveness.11 On the street side, Florida's enforcement entries shift toward products: Amanita stop-sale orders, the Diamond Shruumz recall and a 2026 Miami smoke shop raid. Outside Florida, Oregon (2020) and Colorado (2022) voted in licensed programs that Floridians can travel to.1213

The full timeline

Filter by kind or search for a word such as Fiske, Miami-Dade or trial. Each entry links to the source it was checked against.

85 dated events.

    1. 1970 October 27

      Congress enacts the Controlled Substances Act, which lists psilocybin and psilocyn in Schedule I, the federal category for drugs with a high potential for abuse and no currently accepted medical use in treatment.

      LawUnited StatesSource: 21 U.S. Code 812, Schedules of controlled substances (U.S. Code, GovInfo)

    1. 1971 February 21

      The UN Convention on Psychotropic Substances is concluded. The U.S. Supreme Court later described it as a treaty signed by the United States and implemented by the Controlled Substances Act.

      LawInternationalSource: Gonzales v. O Centro, 546 U.S. 418 (2006), U.S. Reports

    1. 1973 1973

      Florida enacts ch. 73-331. Section 3 of that law is the first entry in the history of section 893.03, the Florida drug schedules that today list psilocybin and psilocyn in Schedule I.

      LawFloridaSource: Florida Statutes 893.03, history note (Florida Senate, 2026)

    1. 1978 December 21

      In Fiske v. State, the Florida Supreme Court, 4-3, reverses a Collier County conviction for possessing wild mushrooms that contained psilocybin, because the statute gave that defendant no fair warning. It also says there is "no vagueness problem with the statute on its face."

      CourtsFloridaSource: Fiske v. State, 366 So. 2d 423 (Fla. 1978), Justia

    1. 1985 August 15

      The Kansas Court of Appeals holds that Kansas's psilocybin statutes, which don't name mushrooms, aren't unconstitutionally vague. It distinguishes Fiske because the Florida case had no evidence the defendant knew the mushrooms contained psilocybin (10 Kan. App. 2d 569, 704 P.2d 1012).

      CourtsKansasSource: 10 Kan. App. 2d 569, 704 P.2d 1012 (Kan. Ct. App. 1985), Caselaw Access Project

    1. 1989 1989

      In the summer of 1989, an administrative order of the chief judge of Florida's 11th Judicial Circuit starts Miami-Dade's drug court. The National Institute of Justice later wrote that the order "set the first drug court in motion."

      PolicyMiami-Dade CountySource: The Drug Court Movement, NIJ Update, National Institute of Justice (September 1995)

    1. 1993 November 16

      Congress enacts the Religious Freedom Restoration Act, which bars government from substantially burdening a person's exercise of religion, even through a rule of general applicability, unless it shows the burden furthers a compelling interest by the least restrictive means.

      LawUnited StatesSource: Public Law 103-141, Religious Freedom Restoration Act of 1993, 107 Stat. 1488 (GovInfo)

    1. 1995 June 22

      The Indiana Court of Appeals distinguishes Fiske, noting that Indiana's statute requires proof that the defendant knew what he had, while in Fiske there was no evidence the defendant knew he possessed illegal mushrooms (652 N.E.2d 89).

      CourtsIndianaSource: 652 N.E.2d 89 (Ind. Ct. App. 1995), Caselaw Access Project

    1. 1996 September 18

      Florida's Fourth District Court of Appeal decides an appeal in a one-line opinion, "Affirmed based on the authority of Fiske v. State," that states no facts (679 So. 2d 363). The reported caption lists the State as appellant, but the attorney listing names the Public Defender as counsel for the appellant, so which side appealed is unclear.

      CourtsFloridaSource: 679 So. 2d 363 (Fla. 4th DCA 1996), Caselaw Access Project

    2. 1996 December 4

      The Fourth District again affirms in a one-line opinion that cites only Fiske and states no facts (683 So. 2d 657). Its caption and attorney listing conflict in the same way about which side appealed.

      CourtsFloridaSource: 683 So. 2d 657 (Fla. 4th DCA 1996), Caselaw Access Project

    1. 1997 June 18

      The Iowa Supreme Court calls Fiske "non-persuasive" where a defendant's knowledge is established (564 N.W.2d 817).

      CourtsIowaSource: 564 N.W.2d 817 (Iowa 1997), Caselaw Access Project

    2. 1997 June 25

      In City of Boerne v. Flores, the U.S. Supreme Court holds that the federal RFRA exceeds Congress's power under the Fourteenth Amendment as applied to the states, so that law doesn't limit state laws.

      CourtsUnited StatesSource: City of Boerne v. Flores, 521 U.S. 507 (1997), U.S. Reports (Library of Congress)

    1. 1998 1998

      Florida enacts its own Religious Freedom Restoration Act (ch. 98-412), which says nothing in it "shall be construed to circumvent the provisions of chapter 893," the state drug law.

      LawFloridaSource: Florida Statutes 761.05 (Florida Senate, 2026)

    1. 2002 2002

      Florida enacts section 893.101, which makes lack of knowledge of a drug's illicit nature an affirmative defense instead of an element the State must prove.

      LawFloridaSource: Florida Statutes 893.101 (Florida Senate, 2026)

    1. 2006 February 21

      In Gonzales v. O Centro, the U.S. Supreme Court rules 8-0 that the federal government hadn't shown, at the preliminary injunction stage, a compelling interest in barring one church's sincere sacramental use of hoasca, a tea containing DMT.

      CourtsUnited StatesSource: Gonzales v. O Centro, 546 U.S. 418 (2006), U.S. Reports

    1. 2012 2012

      Florida creates its 911 Good Samaritan overdose law, section 893.21 (ch. 2012-36). As amended, it protects a person who seeks medical help for an overdose, and the person overdosing, from arrest, charge, prosecution or penalty for listed drug and paraphernalia possession offenses when the evidence was obtained because help was sought.

      LawFloridaSource: Florida Statutes 893.21 (Florida Senate, 2026)

    2. 2012 January

      A MAPS-sponsored Phase 2 study of psilocybin-assisted psychotherapy for anxiety in people with stage IV melanoma lists a January 2012 start at Mount Sinai Comprehensive Cancer Center in Miami Beach. The registry shows it was withdrawn without enrolling anyone.

      ResearchMiami-Dade CountySource: ClinicalTrials.gov NCT00979693

    3. 2012 July 12

      The Florida Supreme Court upholds section 893.101, holding that the Legislature did not violate due process by making lack of knowledge an affirmative defense to chapter 893 offenses (96 So. 3d 412).

      CourtsFloridaSource: 96 So. 3d 412 (Fla. 2012), Caselaw Access Project

    1. 2016 December 1

      The University of Miami's IDEA Exchange opens, which the university describes as the first pilot syringe services program in Florida.

      PolicyMiami-Dade CountySource: About Us, IDEA Exchange, University of Miami Miller School of Medicine

    1. 2017 August 21

      Soul Quest Church of Mother Earth, an Orlando church that uses ayahuasca (a DMT tea, not psilocybin), petitions the DEA for a religious exemption from the Controlled Substances Act.

      PolicyOrlando, FloridaSource: Soul Quest Church of Mother Earth v. DEA, No. 22-11052 (11th Cir. 2024)

    1. 2018 2018

      FDA grants Breakthrough Therapy designation to psilocybin for treatment-resistant depression (COMPASS Pathways). FDA says such a designation isn't a finding of safety or effectiveness.

      ResearchUnited StatesSource: FDA notice of public hearing on psychedelic drugs, 91 FR 43095 (July 14, 2026)

    1. 2019 October 1

      Florida's ch. 2019-167 takes effect. For adults convicted of drug possession or sale, it replaces a 1-year driver license revocation with a 6-month suspension; both versions add "or until" the person is evaluated and completes any required treatment.

      LawFloridaSource: Laws of Florida, ch. 2019-167 (Florida Department of State)

    2. 2019 November 22

      Usona Institute announces that FDA has granted Breakthrough Therapy designation to its psilocybin program for major depressive disorder.

      ResearchUnited StatesSource: FDA grants Breakthrough Therapy Designation to Usona Institute's psilocybin program for major depressive disorder, Usona Institute (November 22, 2019)

    1. 2020 2020

      Oregon voters approve Measure 109, the Oregon Psilocybin Services Act, which licenses supervised psilocybin sessions for adults 21 and over at service centers.

      LawOregonSource: Oregon Revised Statutes chapter 475A (Oregon Legislature)

    2. 2020 January 23

      Usona Institute's Phase 2 psilocybin trial for major depressive disorder starts, with a site at Segal Trials in Lauderhill.

      ResearchBroward CountySource: ClinicalTrials.gov NCT03866174

    3. 2020 February 17

      University of Miami researchers announce $1.624 million from Tassili Life Sciences to study a CBD and psilocybin combination for mild traumatic brain injury and PTSD, starting with animal research.

      ResearchMiami-Dade CountySource: InventUM, University of Miami Miller School of Medicine (February 17, 2020)

    1. 2021 January 28

      Rep. Michael Grieco files HB 549, the "Florida Psilocybin Mental Health Care Act," which would have created a state-licensed psilocybin services program for adults 21 and over.

      PolicyFloridaSource: HB 549 (2021), Use of Psilocybin for Mental Health Treatment, Florida Senate

    2. 2021 April 16

      The DEA denies Soul Quest's religious exemption petition, saying the church hadn't shown that its members' beliefs were sincerely held or that its ayahuasca use was religious exercise, and citing compelling interests in public safety and preventing diversion.

      PolicyOrlando, FloridaSource: Soul Quest Church of Mother Earth v. DEA, No. 22-11052 (11th Cir. 2024)

    3. 2021 April 30

      HB 549 dies in the House Professions & Public Health Subcommittee, its first committee, without a hearing. It had no Senate companion.

      PolicyFloridaSource: HB 549 (2021), Use of Psilocybin for Mental Health Treatment, Florida Senate

    4. 2021 September 24

      Rep. Michael Grieco files HB 193 and Sen. Lauren Book files SB 348, which would have had the Department of Health study MDMA, psilocybin and ketamine for depression, PTSD and other conditions.

      PolicyFloridaSource: SB 348 (2022), Using Alternative Therapies to Treat Mental Health and Other Medical Conditions, Florida Senate

    1. 2022 March 4

      A federal court in Orlando dismisses Soul Quest's lawsuit against the DEA for lack of jurisdiction, because review of a DEA final decision belongs in a federal court of appeals.

      CourtsOrlando, FloridaSource: Order, No. 6:20-cv-701 (M.D. Fla. March 4, 2022), CourtListener

    2. 2022 March 14

      HB 193 and SB 348 die in their first committees without a hearing.

      PolicyFloridaSource: HB 193 (2022), Florida Senate

    3. 2022 March 16

      TRYP Therapeutics starts a single-site, open-label Phase 2a study of psilocybin (TRP-8802) with psychotherapy for binge eating disorder at the University of Florida in Gainesville; it enrolled 5 people.

      ResearchGainesville, FloridaSource: ClinicalTrials.gov NCT05035927

    4. 2022 November 8

      Colorado voters pass Proposition 122, 1,296,992 to 1,121,124, creating a regulated natural medicine access program for supervised care for adults 21 and over.

      LawColoradoSource: Proposition 122, 2022 general election official results, Colorado Secretary of State

    5. 2022 December 7

      Florida's Department of Agriculture and Consumer Services visits a Tampa hemp dispensary and places a stop-sale on its Amanita muscaria products, having found a "poisonous or deleterious substance" under state food-safety law, the owner wrote, as reported by Miami New Times. Amanita muscaria isn't listed in Florida's drug schedules.

      EnforcementTampa, FloridaSource: Florida's First "Magic Mushroom" Dispensary Halts Sales, Miami New Times (January 17, 2023)

    1. 2023 January 24

      COMPASS Pathways starts COMP005, a Phase 3 trial of its psilocybin drug COMP360 for treatment-resistant depression, with sites listed in Orlando and Tampa.

      ResearchFloridaSource: ClinicalTrials.gov NCT05624268

    2. 2023 January 30

      COMPASS Pathways starts a Phase 2 COMP360 trial for recurrent major depressive disorder with a site in Jacksonville.

      ResearchJacksonville, FloridaSource: ClinicalTrials.gov NCT05733546

    3. 2023 February 14

      COMPASS Pathways starts COMP006, a Phase 3 COMP360 trial for treatment-resistant depression, with Florida sites including Miami, Miami Lakes, Lauderhill and West Palm Beach.

      ResearchMiami-Dade CountySource: ClinicalTrials.gov NCT05711940

    4. 2023 May 31

      A KFF Health News report published by WUSF says Florida regulators have cited five businesses, in Daytona Beach, Largo, Plant City, Tallahassee and Tamarac, over Amanita muscaria products since early February, according to state agriculture department records.

      EnforcementFloridaSource: Mood-altering mushroom sales bloom despite Florida and federal safety concerns, WUSF (May 31, 2023)

    5. 2023 July 1

      Testing products used solely to detect fentanyl or listed fentanyl-related substances, such as fentanyl test strips, stop counting as drug paraphernalia in Florida under CS/SB 164 (ch. 2023-297), approved June 27, 2023. Products that measure quantity, weight or potency aren't covered.

      LawFloridaSource: SB 164 (2023), Controlled Substance Testing, Florida Senate

    6. 2023 August 21

      The News Service of Florida reports that the state agriculture department sued a Tallahassee business in Leon County circuit court to enforce a subpoena about Amanita muscaria products, calling the mushroom an "unsafe food or food additive."

      EnforcementTallahassee, FloridaSource: News Service of Florida report via WMNF (August 21, 2023)

    7. 2023 September 1

      The Martin County Sheriff's Office arrests an employee of a Jensen Beach mall store accused of selling psilocybin mushrooms from the store after an undercover purchase, according to the Miami Herald.

      EnforcementMartin CountySource: Miami Herald report via AOL (October 5, 2023)

    8. 2023 December 13

      Sen. Jay Collins requests $3,000,000 for a USF Health clinical trial of psilocybin for PTSD in veterans (Senate funding request 2851).

      PolicyFloridaSource: FY 2024-25 Local Funding Initiative Request 2851, Florida Senate

    9. 2023 December 18

      The Eleventh Circuit, over a dissent, affirms dismissal of Soul Quest's suit, holding that challenges to the DEA's denial had to go straight to a court of appeals under 21 U.S.C. 877.

      CourtsFloridaSource: Soul Quest Church of Mother Earth v. Attorney General, No. 22-11072 (11th Cir. 2023)

    1. 2024 January 2

      A DEA letter says mushroom spores that contain no psilocybin or psilocin are not controlled under federal law, but material that does contain them is.

      PolicyUnited StatesSource: DEA letter on psilocybin mushroom spores (January 2, 2024), DocumentCloud

    2. 2024 February

      The Florida Senate's budget bill carries $650,000 for the USF psilocybin study in veterans with PTSD, after an amendment cut it from $1,000,000.

      PolicyFloridaSource: SB 2500 (2024), engrossed text, Florida Senate

    3. 2024 February 27

      The Eleventh Circuit dismisses Soul Quest's petition for review of the DEA denial as untimely, about 10 months late, without reaching the merits.

      CourtsFloridaSource: Soul Quest Church of Mother Earth v. DEA, No. 22-11052 (11th Cir. 2024)

    4. 2024 March 13

      Cybin announces that FDA has granted Breakthrough Therapy designation to CYB003, its deuterated psilocin drug candidate, which the company, now doing business as Helus Pharma, calls HLP003.

      ResearchUnited StatesSource: Cybin Inc. (doing business as Helus Pharma), management's discussion and analysis, SEC filing (August 14, 2026)

    5. 2024 March 13

      Usona Institute's Phase 3 psilocybin trial for major depressive disorder starts, with Florida sites in Jacksonville, Lauderhill and Orlando.

      ResearchFloridaSource: ClinicalTrials.gov NCT06308653

    6. 2024 May 30

      GAO reports that 24 petitioners sought DEA religious exemptions from fiscal year 2016 through January 2024 and none had been granted; of 6 psilocybin petitions, 3 were withdrawn and 3 were pending.

      PolicyUnited StatesSource: GAO-24-106630, U.S. Government Accountability Office

    7. 2024 June 12

      The Governor approves Florida's 2024-25 budget (ch. 2024-231). It contains no psilocybin funding; the Senate's USF study line didn't survive.

      PolicyFloridaSource: HB 5001 (2024), General Appropriations Act, enrolled text, Florida Senate

    8. 2024 June 27

      Diamond Shruumz chocolate bars, cones and gummies are recalled. FDA's outbreak page later listed 180 illnesses (118 involving Diamond Shruumz products), 6 of them in Florida, and FDA testing found psilocin, muscimol and other substances in some samples.

      EnforcementUnited StatesSource: FDA outbreak investigation: Diamond Shruumz-brand chocolate bars, cones and gummies

    9. 2024 December 17

      Cybin starts APPROACH, a Phase 3 trial of CYB003 for major depressive disorder, with Florida sites including Miami, North Miami and Hollywood.

      ResearchMiami-Dade CountySource: ClinicalTrials.gov NCT06564818

    10. 2024 December 18

      FDA says Amanita muscaria and its constituents muscimol, ibotenic acid and muscarine are not authorized in conventional food, and recommends people avoid foods containing them.

      PolicyUnited StatesSource: FDA constituent update on Amanita muscaria in food (December 18, 2024)

    1. 2025 February 18

      Sen. Jay Collins again requests $3,000,000 for a USF psilocybin trial in veterans with PTSD (Senate funding request 1393). The 2025-26 budget the Governor approved (ch. 2025-198) contains no psilocybin funding.

      PolicyFloridaSource: FY 2025-26 Local Funding Initiative Request 1393, Florida Senate

    2. 2025 June

      The first psilocybin administration sessions begin at Colorado's licensed healing centers, according to the state's Department of Revenue.

      PolicyColoradoSource: Annual Natural Medicine Implementation Report, Colorado Department of Revenue (February 2, 2026)

    3. 2025 June 20

      New Mexico's Medical Psilocybin Act takes effect; the Department of Health says the program is set to be implemented by December 31, 2026.

      LawNew MexicoSource: Medical Psilocybin Program, New Mexico Department of Health

    4. 2025 June 25

      NBC 6 reports that Miami Beach police found suspected psilocybin mushrooms with cocaine, ketamine, fentanyl and other drugs in a Miami Beach apartment; a man was arrested on drug trafficking and child abuse charges.

      EnforcementMiami-Dade CountySource: NBC 6 South Florida (June 25, 2025)

    5. 2025 July 1

      Florida's section 500.75 takes effect, making it a first-degree misdemeanor to transport, import, sell, furnish or give away mushroom spores or mycelium that will produce psilocybin or psilocyn; possession isn't listed. It came from CS/CS/CS/SB 700 (ch. 2025-22), approved by the Governor May 15, 2025.

      LawFloridaSource: CS/CS/CS/SB 700 (2025), Florida Senate

    6. 2025 July 18

      Cybin starts EXTEND, a long-term extension study of CYB003 open by invitation, with Florida sites including Hollywood and Lauderhill.

      ResearchBroward CountySource: ClinicalTrials.gov NCT06605105

    7. 2025 August 12

      Florida's Attorney General issues emergency rule 2ER25-1, adding 7-hydroxymitragynine (7-OH), a kratom-derived compound, to Schedule I when concentrated above 1 percent by total weight.

      LawFloridaSource: Rule 2ER25-1, Florida Administrative Register

    8. 2025 November 4

      Florida's Attorney General announces Operation Slow N Go, led by the Palm Beach County Sheriff's Office and the Office of Statewide Prosecution, against a ring operating in Miami-Dade and six other Florida counties. The release says it uncovered trafficking in psilocybin among other drugs and lists 5 arrests and 23 charges, none naming psilocybin.

      EnforcementFloridaSource: Attorney General press release (November 4, 2025)

    9. 2025 December 10

      Cybin starts EMBRACE, a second Phase 3 trial of CYB003 for major depressive disorder, recruiting in Jacksonville, Maitland, Naples and Tampa.

      ResearchFloridaSource: ClinicalTrials.gov NCT06793397

    1. 2026 March 13

      NBC 6 reports that City of Miami police made an undercover purchase and served a SWAT search warrant at a Miami smoke shop, seizing suspected psilocybin edibles, psilocybin and suspected 7-OH; one man was arrested.

      EnforcementMiami-Dade CountySource: NBC 6 South Florida (March 13, 2026)

    2. 2026 March 25

      WQCS reports that an Okeechobee County traffic stop near a music festival turned up dried mushrooms and mushroom chocolate; one person was charged with possession with intent to sell psilocybin, among other charges.

      EnforcementOkeechobee CountySource: WQCS (March 25, 2026)

    3. 2026 March 31

      Oregon's quarterly psilocybin data for January 2025 through March 2026 add up to 2,114 client responses from people living elsewhere in the U.S. (repeat clients may be counted more than once).

      PolicyOregonSource: Psilocybin Data Archive, Oregon Health Authority

    4. 2026 April

      FDA issues national priority vouchers to companies studying psilocybin for treatment-resistant depression and for major depressive disorder. FDA says a voucher isn't a determination of safety or effectiveness.

      PolicyUnited StatesSource: FDA notice of public hearing on psychedelic drugs, 91 FR 43095 (July 14, 2026)

    5. 2026 April 9

      A CDC report counts 180 illnesses in 34 states, 73 hospitalizations and 2 deaths tied to Diamond Shruumz and other brands' mushroom chocolate products in 2024. FDA's own page counts 3 potentially associated deaths.

      ResearchUnited StatesSource: CDC Morbidity and Mortality Weekly Report 75(13) (April 9, 2026)

    6. 2026 April 18

      Executive Order 14401 directs at least $50 million in existing funds, through ARPA-H, to support states that have enacted or are developing programs to advance psychedelic drugs for serious mental illness, and directs a prompt rescheduling review of any Schedule I product that completes Phase 3 trials for a serious mental health disorder.

      PolicyUnited StatesSource: Executive Order 14401, 91 FR 21709 (April 22, 2026)

    7. 2026 June 16

      The Governor approves CS/SB 432 (ch. 2026-148). Its section 3 rewrites the part of Florida's Schedule I that lists psilocybin and psilocyn, to exempt FDA-approved xylazine animal drug products used as approved. Psilocybin and psilocyn stay listed, unchanged.

      LawFloridaSource: CS/SB 432 (2026), Intoxicating Substances, Florida Senate

    8. 2026 June 22

      Florida's Attorney General signs an emergency rule, effective immediately, expanding Schedule I control to compounds related to concentrated 7-OH.

      LawFloridaSource: Attorney General press release (June 22, 2026)

    9. 2026 July 1

      Testing products used solely to detect xylazine join the fentanyl test-strip exclusion from Florida's definition of drug paraphernalia under CS/HB 477 (ch. 2026-157), approved June 16, 2026. Products that measure quantity, weight or potency still aren't excluded.

      LawFloridaSource: HB 477 (2026), Drug Paraphernalia, Florida Senate

    10. 2026 July 14

      FDA publishes its final guidance "Psychedelic Drugs: Considerations for Clinical Investigations," which gives general considerations for sponsors running clinical trials of psychedelic drugs.

      PolicyUnited StatesSource: Psychedelic Drugs: Considerations for Clinical Investigations; Guidance for Industry; Availability, 91 FR 43101 (July 14, 2026)

    11. 2026 September

      ClinicalTrials.gov lists September 2026 as the estimated start of COMPASS Pathways' Redefine study, a Phase 2/3 trial of COMP360 for PTSD, and shows it recruiting at sites in Miami and Orlando.

      ResearchMiami-Dade CountySource: ClinicalTrials.gov NCT07570654

    12. 2026 September 23

      DEA proposes placing five tryptamine hallucinogens, including 4-OH-DiPT and 5-MeO-DET, in Schedule I; comments closed October 23, 2026. The proposal doesn't cover psilocybin, and Florida's Schedule I already lists four of the five by name.

      PolicyUnited StatesSource: Proposed rule, 91 FR 60338 (September 23, 2026)

    13. 2026 October 5

      The Tenth Circuit orders a federal trial court to vacate its injunction against Utah's criminal prosecution of the founder of Singularism, a religion whose ceremony includes psilocybin. It holds that the trial court should have abstained and erred in finding a likely First Amendment violation.

      CourtsUtahSource: Opinion in No. 25-4115 (10th Cir. October 5, 2026), court filing via Justia

    14. 2026 October 6

      FDA asks for public comment on approaches it is considering for early-phase ibogaine trials, citing heart rhythm risks. HHS is funding ibogaine research, and the first federally supported trials are expected to study opioid use disorder and PTSD.

      PolicyUnited StatesSource: Request for information, 91 FR 63563 (October 6, 2026)

    15. 2026 October 23

      Cybin's APPROACH Phase 3 trial of CYB003, whose sites included Miami, North Miami and Hollywood, is completed, according to ClinicalTrials.gov; no results had been posted to the registry as of November 2, 2026.

      ResearchMiami-Dade CountySource: ClinicalTrials.gov NCT06564818

    16. 2026 October 30

      Colorado's Natural Medicine Division lists 47 approved healing center licenses as of this date: 12 standard and 35 micro.

      PolicyColoradoSource: Natural Medicine Division home page, Colorado Department of Revenue

    17. 2026 November 3

      Scheduled: Florida's general election is set for this date. The statewide ballot carries three proposed constitutional amendments, all placed there by the Legislature; none concerns psilocybin or any other drug.

      PolicyFloridaSource: Constitutional amendments and initiatives, 2026 general election, Florida Division of Elections

    18. 2026 November 4

      Scheduled: Colorado's Natural Medicine Division plans a final rulemaking hearing on natural medicine rules; written comments on its rulemaking to carry out HB26-1325 are also due November 4.

      PolicyColoradoSource: Rulemaking, Colorado Natural Medicine Division

    19. 2026 November 17

      Scheduled: The Florida Senate is set to convene for its organization session, 14 days after the general election, for the exclusive purpose of organization and selection of officers.

      PolicyFloridaSource: 2026-2027 Interim Committee Meeting Schedule, Florida Senate (August 3, 2026)

    20. 2026 November 20

      Scheduled: Public comments are due on FDA's request for information on ibogaine trial design.

      PolicyUnited StatesSource: Request for information, 91 FR 63563 (October 6, 2026)

    21. 2026 December 31

      Scheduled: New Mexico's Department of Health says its medical psilocybin program is set to be implemented by this date; the Medical Psilocybin Act's legal deadline is December 31, 2027.

      PolicyNew MexicoSource: Medical Psilocybin Program, New Mexico Department of Health

    1. 2027 March 2

      Scheduled: Florida's 2027 regular session is set to convene; noon that day is the Senate's deadline for filing bills, and April 30, 2027 is set as the session's last day.

      PolicyFloridaSource: 2027 Regular Session Dates, Florida Senate

Download this data. Psilocybin in Florida: a dated timeline: 85 rows, updated November 2, 2026. Free to reuse under CC BY 4.0 with a link to this page.

What's coming up?

The Florida Senate convenes on November 17, 2026 to organize after the election.14 The 2027 regular session runs from March 2 to April 30, 2027, and noon on March 2 is the Senate's deadline for filing bills.15 Any change to Florida's psilocybin law would have to start as a bill in that session. Our bill tracker will list anything filed.

How is the timeline maintained?

  • One event, one source. Each row has a date, a kind, a place, one or two plain sentences and the source we checked: a statute, bill page, court opinion, registry record or agency page where one exists, and a named news outlet when only a news report covers it.
  • Dates are as precise as the source. When a source gives only a month or a year, the entry shows only that, and the data file says so in a "precision" field.
  • Scheduled events are labeled. Upcoming dates start with "Scheduled" and carry "status": "scheduled" in the data. We update them after they happen.
  • No private names. Arrests and raids appear without the names of the people involved or the street addresses of businesses, and charges are allegations, not convictions.
  • What's left out. Bills that only reprint Florida's drug schedules are left out unless they matter to psilocybin, along with events we couldn't confirm in a source we could open, and events whose only source link no longer works.

The full data set downloads as CSV or JSON under a CC BY 4.0 license. If you spot an error or a missing event, tell us through the contact page and include the source.

Questions people ask

When did psilocybin become illegal in Florida?

Federally, it has been Schedule I since the Controlled Substances Act of October 27, 1970.1 The history note to section 893.03 begins with ch. 73-331 (1973), and the 1975 statutes already listed psilocybin in Schedule I, according to the Fiske opinion.23

Has Florida ever passed a law allowing psilocybin therapy?

No. Since 2019, the only bills that proposed it or a state study (HB 549 in 2021, HB 193 and SB 348 in 2022) died in committee, and no enacted budget since then has included a psilocybin research line.568

Can I reuse this timeline?

Yes. The CSV and JSON files are licensed CC BY 4.0, so you can republish them with credit to Magic Mushrooms Miami. Each row keeps its source link.

Sources

  1. 21 U.S. Code 812, Schedules of controlled substances, Legal Information Institute, Cornell Law School.
  2. Florida Statutes 893.03, Standards and schedules, Florida Senate, 2026.
  3. Fiske v. State, 366 So. 2d 423 (Fla. 1978), Supreme Court of Florida, December 21, 1978 (Justia).
  4. 96 So. 3d 412 (Fla. 2012), Supreme Court of Florida, July 12, 2012, Caselaw Access Project.
  5. HB 549 (2021), Use of Psilocybin for Mental Health Treatment, Florida Senate.
  6. SB 348 (2022), Using Alternative Therapies to Treat Mental Health and Other Medical Conditions, Florida Senate.
  7. SB 2500 (2024), Appropriations, engrossed text, Florida Senate, February 2024.
  8. Local Funding Initiative Request 1393, USF Psilocybin Study in Veterans with PTSD, Florida Senate, February 18, 2025.
  9. CS/CS/CS/SB 700 (2025), Department of Agriculture and Consumer Services, Florida Senate.
  10. Redefine Study (COMP202), NCT07570654, ClinicalTrials.gov, checked November 2, 2026.
  11. Notice of public hearing on the potential future therapeutic use of psychedelic drugs, 91 FR 43095, Food and Drug Administration, July 14, 2026.
  12. Oregon Revised Statutes chapter 475A, Oregon Legislature.
  13. Natural Medicine consumer guide, Colorado Department of Regulatory Agencies.
  14. 2026-2027 Interim Committee Meeting Schedule, Florida Senate, Office of the Secretary, August 3, 2026.
  15. 2027 Regular Session Dates, Florida Senate, August 2026.

Keep reading

Reported and checked by the Magic Mushrooms Miami desk. Every fact on this page links to its source. Spot an error? Tell us and we'll correct it in the open, as our editorial standards explain. Magic Mushrooms Miami is published by the team that runs My Mushroom Dispensary, an online shop. We sell no advertising, and nothing is for sale on this site.